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An in vivo communication study including the coadministration under steady-state conditions of paroxetine and terfenadine, a substrate for cytochrome CYP3A4, disclosed no effect of paroxetine on terfenadine pharmacokinetics.

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“In flexible‑dose studies, no new damaging events were noted in clients obtaining 60 milligrams of Paxil compared with any of the various other therapy groups.”

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Paroxetine could enter boob milk and may harm a nursing child.